eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| testicular cancer | ||||
| Disease ID | 805 |
|---|---|
| Disease | testicular cancer |
| Definition | Testicles, or testes, make male hormones and sperm. They are two egg-shaped organs inside the scrotum, the loose sac of skin behind the penis. You can get cancer in one or both testicles. Testicular cancer mainly affects young men between the ages of 20 and 39. It is also more common in men who
Symptoms include pain, swelling, or lumps in your testicles or groin area. Doctors use a physical exam, lab tests, imaging tests, and a biopsy to diagnose testicular cancer. Most cases can be treated, especially if found early. Treatment options include surgery, radiation, and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility. If you may want children later on, you should consider sperm banking before treatment. NIH: National Cancer Institute |
| Synonym | cancer of testis cancer of the testes cancer of the testis cancer testicle cancer testicles cancer testicular cancer testis cancer, testicular cancer, testis cancers, testicular cancers, testis malignant neoplasm of testis malignant neoplasm of testis nos malignant neoplasm of testis nos (disorder) malignant neoplasm of testis, nos malignant neoplasm of the testis malignant testicular neoplasm malignant testicular tumor malignant tumor of testis malignant tumor of testis (disorder) malignant tumor of the testis malignant tumour of testis testicle cancer testicular cancers testis cancer testis cancers testis neoplasm malignant testis--cancer |
| DOID | |
| UMLS | C0153594 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:30) C0021359 | infertility | 4 C0242350 | erectile dysfunction | 2 C0040053 | thrombus | 2 C0036202 | sarcoidosis | 2 C0011570 | depression | 2 C0036341 | schizophrenia | 2 C0011633 | dermatomyositis | 2 C0007222 | cardiovascular disease | 1 C0024299 | lymphomas | 1 C0153676 | lung metastases | 1 C0004030 | aspergillosis | 1 C0018801 | heart failure | 1 C0085655 | polymyositis | 1 C0033953 | sexual dysfunction | 1 C0042373 | vascular disease | 1 C0004509 | azoospermia | 1 C0014859 | esophageal cancer | 1 C0040053 | thrombosis | 1 C0036631 | seminoma | 1 C0018995 | hemochromatosis | 1 C0021359 | infertile | 1 C0022660 | acute renal failure | 1 C0007873 | cancer of the cervix | 1 C0686619 | lymph node metastases | 1 C0035078 | renal failure | 1 C0264716 | chronic heart failure | 1 C0376358 | prostate cancer | 1 C0033038 | premature ejaculation | 1 C0037856 | testicular torsion | 1 C0003467 | anxiety | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:5) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:18) 367 | AR | CIPHER 8915 | BCL10 | CIPHER 1544 | CYP1A2 | CIPHER 1545 | CYP1B1 | CIPHER 1576 | CYP3A4 | CIPHER 1577 | CYP3A5 | CIPHER 2067 | ERCC1 | CIPHER 2068 | ERCC2 | CIPHER 3119 | HLA-DQB1 | CIPHER 3123 | HLA-DRB1 | CIPHER 3460 | IFNGR2 | CIPHER 3586 | IL10 | CIPHER 4254 | KITLG | CIPHER 4049 | LTA | CIPHER 10743 | RAI1 | CIPHER 5970 | RELA | CIPHER 7040 | TGFB1 | CIPHER 7124 | TNF | CIPHER |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:160) 93 | ACVR2B | 1.753 | DISEASES 174 | AFP | 6.041 | DISEASES 57491 | AHRR | 1.691 | DISEASES 249 | ALPL | 1.234 | DISEASES 250 | ALPP | 2.313 | DISEASES 262 | AMD1 | 1.674 | DISEASES 196527 | ANO6 | 1.697 | DISEASES 367 | AR | 3.367 | DISEASES 545 | ATR | 1.031 | DISEASES 567 | B2M | 2.063 | DISEASES 578 | BAK1 | 3.255 | DISEASES 55589 | BMP2K | 1.732 | DISEASES 689 | BTF3 | 1.495 | DISEASES 100505621 | C11orf72 | 3.555 | DISEASES 153571 | C5orf38 | 2.125 | DISEASES 774 | CACNA1B | 1.084 | DISEASES 778 | CACNA1F | 2.258 | DISEASES 842 | CASP9 | 1.112 | DISEASES 914 | CD2 | 1.124 | DISEASES 29126 | CD274 | 1.099 | DISEASES 8558 | CDK10 | 1.674 | DISEASES 1032 | CDKN2D | 2.19 | DISEASES 3080 | CFHR2 | 2.007 | DISEASES 1106 | CHD2 | 1.984 | DISEASES 9074 | CLDN6 | 1.258 | DISEASES 123920 | CMTM3 | 3.067 | DISEASES 167 | CRISP1 | 2.241 | DISEASES 1443 | CSH2 | 2.251 | DISEASES 10675 | CSPG5 | 1.124 | DISEASES 1485 | CTAG1B | 2.202 | DISEASES 50624 | CUZD1 | 2.095 | DISEASES 1586 | CYP17A1 | 1.509 | DISEASES 1543 | CYP1A1 | 1.188 | DISEASES 1544 | CYP1A2 | 1.293 | DISEASES 1551 | CYP3A7 | 1.335 | DISEASES 10800 | CYSLTR1 | 1.228 | DISEASES 1761 | DMRT1 | 3.792 | DISEASES 373863 | DND1 | 3.615 | DISEASES 26052 | DNM3 | 1.553 | DISEASES 1789 | DNMT3B | 1.009 | DISEASES 1812 | DRD1 | 1.405 | DISEASES 64641 | EBF2 | 1.535 | DISEASES 253738 | EBF3 | 1.502 | DISEASES 8894 | EIF2S2 | 2.359 | DISEASES 955 | ENTPD6 | 2.745 | DISEASES 2051 | EPHB6 | 1.161 | DISEASES 2100 | ESR2 | 2.581 | DISEASES 346653 | FAM71F2 | 3.963 | DISEASES 356 | FASLG | 1.233 | DISEASES 2254 | FGF9 | 1.691 | DISEASES 2274 | FHL2 | 1.179 | DISEASES 668 | FOXL2 | 1.956 | DISEASES 122786 | FRMD6 | 1.153 | DISEASES 2535 | FZD2 | 1.017 | DISEASES 8323 | FZD6 | 1.215 | DISEASES 10146 | G3BP1 | 1.02 | DISEASES 2626 | GATA4 | 1.557 | DISEASES 2668 | GDNF | 2.217 | DISEASES 2674 | GFRA1 | 2.241 | DISEASES 199720 | GGN | 3.911 | DISEASES 2950 | GSTP1 | 1.949 | DISEASES 3006 | HIST1H1C | 1.202 | DISEASES 55355 | HJURP | 1.965 | DISEASES 3292 | HSD17B1 | 2.115 | DISEASES 3293 | HSD17B3 | 1.165 | DISEASES 3295 | HSD17B4 | 2.373 | DISEASES 3320 | HSP90AA1 | 1.252 | DISEASES 3359 | HTR3A | 1.322 | DISEASES 3451 | IFNA17 | 1.217 | DISEASES 3481 | IGF2 | 1.129 | DISEASES 3483 | IGFALS | 1.482 | DISEASES 3486 | IGFBP3 | 1.225 | DISEASES 3615 | IMPDH2 | 1.225 | DISEASES 3640 | INSL3 | 4.818 | DISEASES 56888 | KCMF1 | 2.107 | DISEASES 10765 | KDM5B | 1.848 | DISEASES 9371 | KIF3B | 1.848 | DISEASES 3833 | KIFC1 | 1.448 | DISEASES 3831 | KLC1 | 1.066 | DISEASES 26085 | KLK13 | 2.52 | DISEASES 55554 | KLK15 | 1.122 | DISEASES 9622 | KLK4 | 1.119 | DISEASES 25818 | KLK5 | 2.337 | DISEASES 3875 | KRT18 | 1.106 | DISEASES 3939 | LDHA | 1.019 | DISEASES 378805 | LINC-PINT | 1.102 | DISEASES 4100 | MAGEA1 | 1.06 | DISEASES 4101 | MAGEA2 | 1.03 | DISEASES 266740 | MAGEA2B | 1.033 | DISEASES 4193 | MDM2 | 1.877 | DISEASES 196410 | METTL7B | 1.408 | DISEASES 10724 | MGEA5 | 1.331 | DISEASES 4311 | MME | 1.249 | DISEASES 4326 | MMP17 | 1.516 | DISEASES 4496 | MT1H | 1.482 | DISEASES 4501 | MT1X | 1.382 | DISEASES 9961 | MVP | 1.469 | DISEASES 4609 | MYC | 1.573 | DISEASES 4723 | NDUFV1 | 1.418 | DISEASES 347736 | NME9 | 2.643 | DISEASES 4839 | NOP2 | 1.999 | DISEASES 10718 | NRG3 | 1.238 | DISEASES 113746 | ODF3 | 2.623 | DISEASES 5155 | PDGFB | 1.469 | DISEASES 5241 | PGR | 1.416 | DISEASES 9063 | PIAS2 | 1.525 | DISEASES 5406 | PNLIP | 1.536 | DISEASES 10687 | PNMA2 | 3.764 | DISEASES 5420 | PODXL | 1.406 | DISEASES 64840 | PORCN | 1.065 | DISEASES 5573 | PRKAR1A | 1.742 | DISEASES 5580 | PRKCD | 1.047 | DISEASES 54496 | PRMT7 | 2.05 | DISEASES 58155 | PTBP2 | 1.142 | DISEASES 5744 | PTHLH | 1.219 | DISEASES 5788 | PTPRC | 2.015 | DISEASES 9232 | PTTG1 | 1.911 | DISEASES 5879 | RAC1 | 1.005 | DISEASES 11186 | RASSF1 | 1.28 | DISEASES 5935 | RBM3 | 1.251 | DISEASES 54894 | RNF43 | 1.055 | DISEASES 26766 | RNU105C | 1.646 | DISEASES 9037 | SEMA5A | 1.261 | DISEASES 57515 | SERINC1 | 2.037 | DISEASES 347735 | SERINC2 | 2.501 | DISEASES 6462 | SHBG | 3.227 | DISEASES 9121 | SLC16A5 | 2.709 | DISEASES 83733 | SLC25A18 | 1.166 | DISEASES 11182 | SLC2A6 | 2.195 | DISEASES 1317 | SLC31A1 | 1.194 | DISEASES 4093 | SMAD9 | 1.343 | DISEASES 6605 | SMARCE1 | 1.344 | DISEASES 23583 | SMUG1 | 3.324 | DISEASES 677825 | SNORA44 | 2.063 | DISEASES 64089 | SNX16 | 2.361 | DISEASES 402381 | SOHLH1 | 2.338 | DISEASES 54937 | SOHLH2 | 2.089 | DISEASES 6693 | SPN | 1.196 | DISEASES 10252 | SPRY1 | 1.132 | DISEASES 81848 | SPRY4 | 3.854 | DISEASES 56910 | STARD7 | 1.897 | DISEASES 6794 | STK11 | 1.099 | DISEASES 6949 | TCOF1 | 1.919 | DISEASES 732253 | TDRG1 | 2.664 | DISEASES 10953 | TOMM34 | 1.886 | DISEASES 5987 | TRIM27 | 1.387 | DISEASES 11074 | TRIM31 | 1.335 | DISEASES 80705 | TSGA10 | 2.032 | DISEASES 7258 | TSPY1 | 2.346 | DISEASES 100289087 | TSPY10 | 2.383 | DISEASES 255220 | TXNDC8 | 2.674 | DISEASES 7405 | UVRAG | 1.228 | DISEASES 7490 | WT1 | 2.134 | DISEASES 7503 | XIST | 1.728 | DISEASES 51067 | YARS2 | 1.533 | DISEASES 23414 | ZFPM2 | 1.03 | DISEASES 7702 | ZNF143 | 1.341 | DISEASES 7707 | ZNF148 | 1.316 | DISEASES 23036 | ZNF292 | 2.254 | DISEASES 81931 | ZNF93 | 2.944 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 805 |
|---|---|
| Disease | testicular cancer |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:24) HP:0000028 | Cryptorchidism | 8 HP:0002664 | Neoplasia | 6 HP:0000789 | Infertility | 4 HP:0012215 | Testicular microlithiasis | 2 HP:0100753 | Schizophrenia | 2 HP:0000716 | Depression | 2 HP:0100543 | Cognitive deficits | 2 HP:0012125 | Prostate cancer | 2 HP:0000802 | Erectile dysfunction | 2 HP:0002625 | Blood clot in a deep vein | 1 HP:0012531 | Pain | 1 HP:0001250 | Seizures | 1 HP:0004850 | Recurrent deep vein thrombosis | 1 HP:0000969 | Dropsy | 1 HP:0000083 | Renal insufficiency | 1 HP:0000739 | Anxiety | 1 HP:0012876 | Premature ejaculation | 1 HP:0002181 | Cerebral edema | 1 HP:0100813 | Testicular torsion | 1 HP:0000027 | Azoospermia | 1 HP:0001919 | Acute renal failure | 1 HP:0100728 | Germ cell neoplasia | 1 HP:0012879 | Ejaculatory incompetence | 1 HP:0001635 | Congestive heart failure | 1 |
| Disease ID | 805 |
|---|---|
| Disease | testicular cancer |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:31) C2364072 | depression C1963120 | gynecomastia C1735598 | paraneoplastic dermatomyositis C1378703 | renal cancer C1321542 | azoospermia C1301700 | cardiovascular morbidity C1266157 | intratubular germ cell neoplasia C0868910 | oligozoospermia C0868910 | oligospermia C0746921 | lymph node mass C0700361 | distress C0686619 | lymph node metastases C0521991 | stress symptoms C0497156 | lymphadenopathy C0442874 | neuropathy C0346989 | peritoneal metastases C0345967 | malignant mesothelioma C0338430 | paraneoplastic limbic encephalitis C0333027 | microlithiasis C0220650 | brain metastases C0178829 | genital disorder C0153687 | skin metastasis C0086132 | depressive symptoms C0032461 | polycythemia C0027404 | narcolepsy C0024232 | lymphatic metastases C0021359 | infertility C0020619 | hypogonadism C0014038 | encephalitis C0006118 | brain tumor C0003469 | anxiety disorder |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:6) C0021359 | infertility | 4 C1735598 | paraneoplastic dermatomyositis | 2 C0011570 | depression | 2 C0686619 | lymph node metastases | 1 C1266157 | intratubular germ cell neoplasia | 1 C0004509 | azoospermia | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:9) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs121913506 | NA | 3815 | KIT | umls:C0153594 | CLINVAR | NA | 0.120542884 | NA | KIT | 4 | 54733154 | G | C,T |
| rs137853078 | NA | 6794 | STK11 | umls:C0153594 | CLINVAR | NA | 0.120542884 | NA | STK11 | 19 | 1220396 | G | A |
| rs370432633 | NA | 8915 | BCL10 | umls:C0153594 | CLINVAR | NA | 0.122367032 | NA | BCL10 | 1 | 85267841 | G | A |
| rs4474514 | 19483682 | 4254 | KITLG | umls:C0153594 | GWASCAT | Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. | 0.124538567 | 2009 | KITLG | 12 | 88560182 | G | A |
| rs4474514 | 19483682 | 4254 | KITLG | umls:C0153594 | GAD | [Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.] | 0.124538567 | 2009 | KITLG | 12 | 88560182 | G | A |
| rs4590952 | 25220285 | 4254 | KITLG | umls:C0153594 | BeFree | Recently, a functional polymorphism in KITLG, rs4590952, was identified to be associated with testicular cancer susceptibility through increasing the p53-dependent KITLG expression and disrupting the function of p53. | 0.124538567 | 2014 | KITLG | 12 | 88559882 | A | G |
| rs4590952 | 25220285 | 7157 | TP53 | umls:C0153594 | BeFree | Recently, a functional polymorphism in KITLG, rs4590952, was identified to be associated with testicular cancer susceptibility through increasing the p53-dependent KITLG expression and disrupting the function of p53. | 0.00434307 | 2014 | KITLG | 12 | 88559882 | A | G |
| rs7040024 | 21551455 | 1761 | DMRT1 | umls:C0153594 | GWASCAT | A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. | 0.12 | 2011 | DMRT1 | 9 | 845516 | A | C |
| rs755383 | 21551455 | 1761 | DMRT1 | umls:C0153594 | GWASCAT | A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. | 0.12 | 2011 | DMRT1 | 9 | 863635 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:41) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 2 | 66167064 | rs17031166 | G | C | rs17031166 | 19483682 | 4.98E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 2 | 66167564 | rs1549383 | G | A | rs1549383 | 19483682 | 1.01E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 2 | 66167564 | rs1549383 | G | A | rs1549383 | 21551455 | 3.44E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 2 | 70959327 | rs3755353 | G | A | rs3755353 | 19483682 | 1.77E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 2 | 182377541 | rs3770112 | G | A | rs3770112 | 19483682 | 4.93E-08 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 4 | 128649890 | rs6534637 | A | C | rs6534637 | 19483682 | 1.06E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 4 | 128649890 | rs6534637 | A | C | rs6534637 | 21551455 | 1.15E-07 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 5 | 141663364 | rs12521013 | A | C | rs12521013 | 19483682 | 1.99E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 5 | 141663364 | rs12521013 | A | C | rs12521013 | 21551455 | 2.09E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 5 | 141669507 | rs4324715 | C | T | rs4324715 | 19483682 | 2.72E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 5 | 141687639 | rs6897876 | T | C | rs6897876 | 19483682 | 1.77E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 5 | 141687639 | rs6897876 | T | C | rs6897876 | 21551455 | 1.87E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 6 | 65034184 | rs7774545 | G | A,T | rs7774545 | 19483682 | 1.83E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 7 | 52898154 | rs2965606 | T | A | rs2965606 | 19483682 | 4.78E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 7 | 90385330 | rs10281060 | G | C | rs10281060 | 21551455 | 2.19E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 7 | 90413101 | rs6951213 | G | A | rs6951213 | 21551455 | 2.75E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 7 | 91669808 | rs6961928 | G | A | rs6961928 | 19483682 | 1.83E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 8 | 90331084 | rs4568650 | A | C | rs4568650 | 21551455 | 4.52E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 9 | 845516 | rs7040024 | A | C | rs7040024 | 21551455 | 1.00E-11 | NA | 1.7 | [1.46-1.99] | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs7040024-A | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 9 | 863635 | rs755383 | C | T | rs755383 | 21551455 | 9.00E-10 | NA | 1.5 | [1.32-1.71] | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs755383-T | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 12 | 88847001 | rs7486184 | A | G | rs7486184 | 19483682 | 4.56E-07 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88847001 | rs7486184 | A | G | rs7486184 | 21551455 | 3.95E-07 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 19483682 | 7.47E-09 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 21551455 | 5.78E-10 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 12 | 88951485 | rs1472899 | C | T | rs1472899 | 19483682 | 3.09E-09 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88951485 | rs1472899 | C | T | rs1472899 | 21551455 | 4.08E-10 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88953326 | rs3782179 | C | T | rs3782179 | 19483682 | 1.35E-09 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 12 | 88953326 | rs3782179 | C | T | rs3782179 | 21551455 | 1.82E-10 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 12 | 88953561 | rs3782181 | C | A | rs3782181 | 19483682 | 8.38E-10 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 12 | 88953561 | rs3782181 | C | A | rs3782181 | 21551455 | 1.11E-10 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 12 | 88953959 | rs4474514 | G | A | rs4474514 | 19483682 | 6.00E-15 | NA | 3.07 | [2.29-4.13] | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4474514-A | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88953959 | rs4474514 | G | A | rs4474514 | 21551455 | 7.08E-11 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88956400 | rs11104952 | T | G | rs11104952 | 19483682 | 1.90E-09 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88956400 | rs11104952 | T | G | rs11104952 | 21551455 | 3.58E-10 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 88960727 | rs1352947 | C | T | rs1352947 | 19483682 | 4.24E-09 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 12 | 88960727 | rs1352947 | C | T | rs1352947 | 21551455 | 1.01E-09 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 12 | 89012852 | rs2639101 | A | C | rs2639101 | 21551455 | 1.37E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 13 | 31276728 | rs6490478 | G | T | rs6490478 | 21551455 | 2.56E-07 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 18 | 25237011 | rs7236484 | T | A | rs7236484 | 19483682 | 1.61E-06 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| X | 91162118 | rs2524594 | G | A | rs2524594 | 19483682 | 8.91E-07 | NA | NA | NA | 277 European ancestry cases; 919 European ancestry controls | European(1196) | ALL(1196) | EUR(1196) | ALL(1196) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 124505129 | rs1964186 | C | T | rs1964186 | 21551455 | 3.25E-06 | NA | NA | NA | 349 cases; 919 controls | NOPOP(1268) | ALL(1268) | NOPOP(1268) | ALL(1268) | Testicular cancer | HPOID:0010788 | Testicular neoplasm | DOID:2998 | testicular cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 805 |
|---|---|
| Disease | testicular cancer |
| Case | (Waiting for update.) |